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Participation of valine 171 in α-helix 5 of Bacillus thuringiensis Cry1Ab δ-endotoxin in translocation of toxin into Lymantria dispar midgut membranes

The Cry1Ab δ-endotoxin V171C mutant protein exhibits a 25-fold increase in toxicity against Lymantria dispar, which correlates with a faster rate of partitioning into the midgut membrane and slightly decreased protein stability. This is an insect-specific mechanism; similar results were not observ...

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Bibliographic Details
Institution:Universidad EIA
Main Authors: Alzate, Oscar, Osorio, Cristina, Florez, Alvaro M., Dean, Donald H.
Format: Artículo de revista
Language:English
Published: 2010-10-01
Subjects:
α-helix
δ-endotoxin
Bacillus thuringiensis
Cry1Ab
Online Access:https://repositorio.udes.edu.co/handle/001/3287
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