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An azole tolerant endosomal trafficking mutant of Candida albicans is susceptible to azole treatment in a mouse model of vaginal candidiasis.

We recently reported that a Candida albicans endosomal trafficking mutant continues to grow after treatment with the azole antifungals. Herein, we report that the vps21Δ/Δ mutant does not have a survival advantage over wild-type isolates after fluconazole treatment in a mouse model of vaginal candid...

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Bibliographic Details
Institution:Universidad de Sucre
Main Authors: Peters, Brian M., Luna Tapia, Arturo, Tournu, Héléne, Rybak, Jeffrey M., Rogers, David P., Palmer, Glen E., American Society for Microbiology.
Format: Artículo de revista
Language:English
Published: Estados Unidos Antimicrobial Agents and Chemotherapy, 2017. 2019-09-24
Subjects:
Azoles
Candida albicans
Resistance
Tolerance
Vaginal candidiasis
Vps21p
Online Access:https://repositorio.unisucre.edu.co/handle/001/792
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