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L-Asparaginase from E. chrysanthemi expressed in glycoswitch: effect of Hist-Tag fusion on the extracellular expression.

L-Asparaginase (L-ASNase) is an important enzyme used to treat acute lymphoblastic leukemia, recombinantly produced in a prokaryotic expression system. Exploration of alternatives production systems like as extracellular expression in microorganisms generally recognized as safe (such as Pichia pasto...

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Bibliographic Details
Institution:Universidad de Sucre
Main Authors: Effer, Brian, Meira Lima, Guilherme, Cabarca, Sindy, Pessoa, Adalberto, Farías, Jorge G., Monteiro, Gisele
Format: Artículo de revista
Language:English
Published: Reino Unido: Preparative Biochemistry and Biotechnology, 2019. 2019-10-31
Subjects:
L-Asparaginase
Extracellular expression
Glycoswitch
His-tag
Online Access:https://repositorio.unisucre.edu.co/handle/001/951
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