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A theranostic PSMA ligand for PET imaging and retargeting of T cells expressing the universal chimeric antigen receptor UniCAR

Chimeric antigen receptor (CAR) T cells have shown impressive therapeutic potential. Due to the lack of direct control mechanisms, therapy-related adverse reactions including cytokine release- and tumor lysis syndrome can even become life-threatening. In case of target antigen expression on non-mali...

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Bibliographic Details
Institution:Universidad EIA
Main Authors: Arndt, Claudia, Feldmann, Anja, Koristka, Stefanie, Schäfer, Martin, Bergmann, Ralf, Mitwasi, Nicola, Berndt, Nicole, Bachmann, Dominik, Kegler, Alexandra, Schmitz, Marc, Puentes-Cala, Edinson, Soto, Javier-Andrés, Ehninger, Gerhard, Pietzsch, Jens, Liolios, Christos, Wunderlich, Gerd, Kotzerke, Jörg, Kopka, Klaus, Bachmann, Michael, Taylor & Francis Group
Format: Artículo de revista
Language:English
Published: Taylor & Francis Group 2019-09-07
Edition:1 ed.
Subjects:
PSMA ligand
UniCAR
Prostate cancer
Immunotherapy
PET imaging
Online Access:https://repositorio.udes.edu.co/handle/001/5616
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